Staphylococcal scalded skin syndrome - Stafilokokk Kuygan Teri Sindromi
☆ Germaniyaning 2022 yilgi Stiftung Warentest natijalariga ko'ra, iste'molchilarning ModelDermdan qoniqish darajasi pullik teletibbiyot maslahatlariga qaraganda bir oz pastroq bo'lgan.
Stafilokokk Kuygan Teri Sindromi (Staphylococcal scalded skin syndrome) bo'lgan chaqaloq
References
Staphylococcal Scalded Skin Syndrome - bu stafilokokk bakteriyalarining ayrim turlari tomonidan ishlab chiqarilgan toksinlar tufayli terining to'kilishi holati. Olti yoshdan oshgan bolalarda kamdan-kam uchraydi. Shuningdek, u immuniteti zaiflashgan yoki jiddiy buyrak muammolari bo'lgan kattalarda paydo bo'lishi mumkin. Asosiy xususiyat - yallig'lanishdan keyin terining keng ko'lamli peelingi. Og'irlik darajasi bir nechta pufakchalardan tortib keng tarqalgan terining yo'qolishiga qadar o'zgarib turadi, bu tana haroratining keskin pasayishiga va qon bosimining beqarorligiga olib kelishi mumkin.
Staphylococcal Scalded Skin Syndrome is a disease characterized by denudation of the skin caused by exotoxin producing strains of the Staphylococcus species, typically from a distant site. It usually presents 48 hours after birth and is rare in children older than six years. It may also present in immunocompromised adults or those with severe renal disease. The disorder is characterized by significant exfoliation of skin following cellulitis. The severity may vary from a few blisters to system exfoliation leading to marked hypothermia and hemodynamic instability.
Staphylococcal Scalded Skin Syndrome is a disease characterized by denudation of the skin caused by exotoxin producing strains of the Staphylococcus species, typically from a distant site. It usually presents 48 hours after birth and is rare in children older than six years. It may also present in immunocompromised adults or those with severe renal disease. The disorder is characterized by significant exfoliation of skin following cellulitis. The severity may vary from a few blisters to system exfoliation leading to marked hypothermia and hemodynamic instability.
Staphylococcal scalded skin syndrome (SSSS) and bullous impetigo are infections caused by Staphylococcus aureus. Bullous impetigo is due to the local release of these toxins and thus, often presents with localized skin findings, whereas SSSS is from the systemic spread of these toxins, resulting in a more generalized rash and severe presentation. Both conditions are treated with antibiotics that target S. aureus. These conditions can sometimes be confused with other conditions that result in superficial blistering.
10 oylik bola burnidan oqishi, ovqatlanmasligi bilan keldi. Shifokorlar bu yuqori nafas yo'llarining infektsiyasi ekanligini aytishdi. Ikki kundan so'ng, u yaxshilanmayotgani va yuzning shishishi va og'iz atrofidagi terining tirnash xususiyati kabi yangi muammolarga duch kelgani uchun qaytib keldi. Keyingi ikki kun ichida bolaning ahvoli yomonlashdi. Qo'llari va oyoqlari shishib, terisi tusha boshladi. Kasalxonaga qaytib kelganida shifokorlar uning yuzida va teri burmalarida qizarib ketgan toshmalar paydo bo'lganini payqashgan, ular teginish paytida oqarib ketgan. Ular unga staphylococcal scalded skin syndrome (SSSS) tashxisini qo'yishdi va unga vena orqali antibiotiklar berishni boshladilar.
A 10-month-old male presented with rhinorrhea and decreased oral intake and was diagnosed with an upper respiratory infection. Two days later, he returned to the clinic due to a lack of improvement and the onset of new symptoms, including facial edema and perioral skin irritation. That evening, he became febrile at 100.4 °F and went to the emergency department at the local children's hospital. No further workup was done and the parents were instructed to continue with the current treatment regimen. Over the next 48 hours, the patient's symptoms worsened with the new onset of bilateral extremity edema and desquamation. The patient was returned to the emergency department. A physical exam was notable for a blanching, desquamating, erythematous rash on the face and creases of the arms, legs, and groin. A positive Nikolsky sign was reported. A clinical diagnosis of staphylococcal scalded skin syndrome (SSSS) was made, and the patient was started on intravenous clindamycin. This case illustrates a severe presentation of SSSS in a pediatric patient, demonstrating the challenges it poses to diagnosis and treatment.
A 10-month-old male presented with rhinorrhea and decreased oral intake and was diagnosed with an upper respiratory infection. Two days later, he returned to the clinic due to a lack of improvement and the onset of new symptoms, including facial edema and perioral skin irritation. That evening, he became febrile at 100.4 °F and went to the emergency department at the local children's hospital. No further workup was done and the parents were instructed to continue with the current treatment regimen. Over the next 48 hours, the patient's symptoms worsened with the new onset of bilateral extremity edema and desquamation. The patient was returned to the emergency department. A physical exam was notable for a blanching, desquamating, erythematous rash on the face and creases of the arms, legs, and groin. A positive Nikolsky sign was reported. A clinical diagnosis of staphylococcal scalded skin syndrome (SSSS) was made, and the patient was started on intravenous clindamycin. This case illustrates a severe presentation of SSSS in a pediatric patient, demonstrating the challenges it poses to diagnosis and treatment.
2 yoshli qiz bir kun oldin yuzida hasharotlar chaqishi natijasida butun vujudida 48 soat davomida paydo bo'lgan toshma paydo bo'ldi. Tekshiruv chog'ida uning terisida bir-biriga qo'shilib ketgan mayda bo'laklardan iborat keng tarqalgan toshma paydo bo'lgan, engil ishqalanganda terisida Nikolskiy belgisi belgilari paydo bo'lgan. Uning shilliq qavatiga ta'sir qiladigan toshma belgilari yo'q edi. Uning qonida o‘tkazilgan tahlillar infektsiya belgilarini ko‘rsatmadi.
A 2-year-old girl presented a generalised rash with 48 h of evolution, in the context of insect bites on the face on the day before. At observation, she had a generalised micropapular rash with confluent areas and Nikolsky sign. There was no mucosal area affected. Blood cultures were negative.
A 2-year-old girl presented a generalised rash with 48 h of evolution, in the context of insect bites on the face on the day before. At observation, she had a generalised micropapular rash with confluent areas and Nikolsky sign. There was no mucosal area affected. Blood cultures were negative.
Sindrom S. aureus tomonidan chiqariladigan epidermolitik ekzotoksinlar (eksfoliatin) A va B tomonidan qo'zg'atiladi. Bolalardagi stafilokokk kuygan teri sindromi (staphylococcal scalded skin syndrome) ning prognozi juda yaxshi, davolashdan keyin 10 kun ichida to'liq yo'qoladi va sezilarli chandiqlarsiz. Biroq, stafilokokk kuygan teri sindromi (staphylococcal scalded skin syndrome) ni yomon prognozli toksik epidermal nekrolizdan ehtiyotkorlik bilan ajratish kerak.
○ Diagnoz va davolash
Atopik dermatit kabi ekzema lezyonlari sifatida noto'g'ri tashxis qo'yish va steroid malhamni qo'llash jarohatlarni kuchaytiradi. Antibiotikli malhamni qo'llashda iloji boricha tezroq tibbiy yordamga murojaat qiling.
#Bacitracin
#First-generation cephalosporins (e.g. Cefradine)
#Bacterial culture
#Third-generation cephalosporins (e.g. Cefditoren Pivoxil)